Senescent Cell Cleanup. Blood Is Only Part Of The Solution:
Awhile ago, we told you how our old friend Elizabeth may have really been onto something age-defying in her own dark-ages nutbar kinda way.
Well in a second round of science catching-up, researchers have found another interesting follow-up to that original Bathory hack.
What the Mayo Clinic docs discovered is an interesting Filter-based alternative to simply getting the odd pint from a young person.
-And it all hinges on a type of cell in our body called, Senescent Cells…
Senescent cells are just old cells all throughout our body that have stopped dividing, so they’re just kind-of sitting around.
Static Does Not Necessarily Mean Harmless:
BUT! recently scientists have guessed [correctly] that they’re not just the peaceful old man on a park bench.
They’re more like a sedentary old man on a park bench screaming at passersby and throwing things at them.
Because not only do they accumulate, slow down & just sit there, they very likely are putting out chemicals and metabolites that can damage other cells & tissues.
Your Body Needs A Little “Drano” When Your Immune-System Screws Up:
As you might imagine, the immune system usually cleans these guys up,
-But it’s not always perfect and may decline in effective-cleaning with age.
So that’s where the scientists got their idea. -What if you could Liquid-Plumr your body at the cellular-level?
And so they used a gene-editing trick to give those senescent cells in the test animals an easily-targetable tag.
That way, the drug they used later-on could find & destroy them. Which it did.
And the results were surprising.
The Cleanup Crew Drug’s Astounding Results For Lifespan & Healthspan:
The treated mice’s lifespan increased anywhere from 17 to 35 percent!
More interestingly, those mice were also healthier and more active and inquisitive for longer.
-The last one of these also implies a healthier Brain, even though cognitive tests weren’t conducted.
Their hearts and kidneys were also particularly healthier for longer durations.
And they also developed other diseases later than a typical mouse.
The trick with all of this for Humans is to do something similar without resorting to drastic measures, like going in to edit a person’s dna with a virus.
The Awesome Advantage We Have Over Senescent Cells; -Time:
And what’s even better about this probably simplest life-extender is this:
Senescent cells don’t accumulate that quickly.
So you have a much easier, longer time to get at them, making the odds of success that much better.
-All science has to do now is figure out an existing marker for those cells and a safe way of targeting them,
And BOOM!, your 35% longer, healthier, more sharp-minded life is just a few pills away!
Hope For All The Non-Immortal Jellyfish / Non-Yazemeenah Rossis Among Us:
And that’s great news for the rest of us Mortals who aren’t magical, organic-avocado-eating, perfect-diet specimens,
Like the immortal (probably vampire) Yazemeenah Rossi.
I mean, if nature can do it with some species mystifyingly surviving longer than their cousins,
Then why can’t mankind do it with a clever little Windex for your cells?
• Source: Mayo Clinic
• via: MIT Tech Review
• More Coverage: Nature
• Source Studies:
•Nature-Naturally-Occurring P16-Ink4a-Positive Cells Shorten Healthy Lifespan
•Nature-Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders