Photo: Jan Ranft, Unsplash
Work The Extra Fat Off Just By Taking A Pill, No Snake-Oil Involved!:
When your car is stuck in a rut, you have to either change course to get out of it.
Or just call a professional, and maybe ask them to bring their tow truck.
Although it should happen more slowly, the journey of weight loss can be a very similar process.
You need a perspective that’s different from the rut.
Because somehow you’re supposed to automatically know what to do and be good at it, but it always seems harder and more directionless than it should be.
Well, a team from The University Of Florida may have an answer for you that could even beat Ozempic…
The Short Answer:
- Weight loss can seem a lot more difficult than it should be.
- And if there’s one thing Americans are impatient about, it’s progress.
- Ozempic does about four different things to make people lose weight.
- Several of these center around appetite and cravings.
- The new experimental pill centers around metabolism.
- Obese test mice were given the pill 2x/day for 1 month.
- Over that time, they lost 12% of their body weight and gained 90% less fat than untreated mice.
- This rate is pretty nuts, because 1 lb/week, depending on your size, is more realistic for humans.
- The amazing features of this drug is that it mimics exercise and burns fat.
- The benefits don’t stop there.
- Test mice were able to run 70% longer and 45% farther as well.
- If the pill really does mimic exercise, several other biochemistry benefits may accrue also.
- These include reduced inflammation and lower rates of Alzheimer’s.
- This pill could also be The Holy Grail, because it gets the body to burn fat while retaining muscle.
- That one feature could benefit many audiences; from bodybuilders to senior-citizens.
Read on to find out the details…
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Popping Pills Might Be More Popular Than Healthy Habits:
If you’ve ever tried to get anything done in another part of the world, you realize that Americans do enjoy a certain pace of business.
I won’t go as far as saying you can’t get anything done in Europe because everyone is either on lunch or vacation, but it’s not far off.
And in that spirit, a lot of the innovations we like over here are the ones that save time.
-Like popping pills or taking a shot for something.
Like Ozempic for weight-loss*…
This New Formula Could Be The Ultimate Weight-Loss Drug:
Now there is another contender in the ring, with a different type of mechanism.
What Ozempic does is at least four different things, but it also reduces cravings.
By contrast, the new drug developed by teams from UF and WU-St. Louis is essentially exercise in a bottle.
And if you’ve read the posts here on the many benefits of cardio and weightlifting, that looks like a very good thing!
Weight-Loss That Also Comes With Fringe-Benefits!:
In a month-long trial on obese mice, subjects were given the experimental drug twice a day.
Over that time, they gained only 10% the fat of untreated mice on the same diet.
Furthermore, they lost 12% of their body weight in that same month as well.
For comparison, 1 pound/week is a more realistic and healthy number to try to hit, depending on how much you weigh.
The most astounding part of the weight loss was not just the amount, though.
It was the fact that:
1) It mimics pathways that are similar to endurance exercise
2) It gets the body to burn fat
And the second one is the real killer, because you don’t want to lose muscle or burn only carbs.
You want to burn the stuff you have too much of: stored body fat.
Looks Like Increased Athletic Performance Is On The Menu As Well:
The way it does this is also a breakthrough.
Because the pathways involved are ones that have been difficult to work up until now (called ERRs).
Despite the funny name, they are very important because that part about it being like exercise in a pill is no joke.
The new unpronounceable drug** gets your muscles to act like they’re exercising,
AND somehow subjects also got exercise-boosting benefits, too! -BOOM!
These include:
1) Being able to run 70% longer
2) Being able to run 45% farther
Ozempic may do a lot of things, but it certainly does nothing like that!
What If You Get All The Other Benefits Of Exercise Too?:
I don’t know about you, but if I was going to pop a pill to burn off a little fat, and Pfizer’s puke-inducing Ozempic clone were fixed and available,
I know which one I’d choose.
Now, as is the case with all of these things when they’re new, more trials are necessary.
But one of the other last bits of good news from the study is that so far no side-effects have been observed in the mice subjects.
If the biochemistry of exercise comes into play at all, then there might be even more potential benefits, like:
1) Reduced inflammation everywhere in the body
2) Cleaning out all kinds of junk from the brain like Cardio does
3) Increased brain-cell growth in the memory-centers
4) Improved expression of genes
One More Thing… The Holy Grail:
But wait, there’s one more; The Holy Grail.
As subjects’ metabolism went up, their body switched over to burning fat while on the same type & number of calories.
And this looks like it achieves the Ideal Scenario of losing fat while still keeping muscle-mass on a diet.
Every single person’s absolute dream; bodybuilders included. -BOOM!
So, let’s all keep our fingers-crossed for the next crazy weight-loss pill from the “exercise-mimetic” ERR-pathway-blasting camp!
References & Links:
• Source: UF
• More Coverage: J.SportsSciMed – Effects of Mental Imagery on Muscular Strength in Healthy and Patient Participants: A Systematic Review
• Source Studies:
•J.PharmacolExcTher – A Synthetic ERR Agonist Alleviates Metabolic Syndrome
•JCIM – Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity
*(-Which was ironically invented by at least a few non-Americans and has completely revolutionized the Danish economy.)
**That has a name like Marvin The Martian’s Illudium Q-36 Explosive Space Modulatore.
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